It usually points to the inside of the knee. In a series of 1,001 knee scans, 94 percent of the cysts came with at least one problem inside the joint, the commonest being meniscus tears, often at the back of the inner meniscus, and cartilage damage (Sansone et al., 1995). In another series, extra joint fluid, a meniscus tear and arthritis were each linked with cysts independently of one another, and the more of them a knee had, the more likely a cyst was: 38 percent of knees with all three had one (Miller et al., 1996).
It can turn up in knees that do not hurt. On MRI, about one in five painless knees had a cyst in one study, most of them 3 cm or smaller (Tschirch et al., 2003). In older adults, cysts were found in 28 percent of painless knees with arthritis on X-ray and 9 percent of painless knees with a normal X-ray (Hill et al., 2001). The figures vary with age, with who is scanned and with the type of scan: in another study, none of 100 people without knee complaints had a cyst on ultrasound (Rupp et al., 2002).
It is usually not the whole explanation for the pain. Studies differ on how much a cyst adds to knee pain. In those older adults, once the severity of arthritis was taken into account, painful knees did not have cysts more often than painless ones, though they did have more joint fluid and a thicker joint lining (Hill et al., 2001). On the other hand, among people with arthritis bad enough for a knee replacement, 71 percent had symptoms from the cyst (Hommel et al., 2016). A large cyst can give a feeling of fullness or tightness behind the knee, particularly when the knee bends fully.
What keeps it filled matters more. The report names the cyst because it can be seen. What matters is what keeps it filled, and that is usually in the other lines of the same report, about the menisci, the cartilage and the joint fluid, and in how your knee behaves.