The Science of Osteoarthritis of the Knee

Osteoarthritis involves breakdown of cartilage, changes in underlying bone, and inflammation of the joint lining. It's not just wear and tear but an active process involving the whole joint. Muscle weakness, particularly quadriceps, accelerates progression. Previous injuries such as ACL tears or meniscus tears significantly increase the risk of developing knee osteoarthritis, as these injuries often lead to altered biomechanics and joint instability. Like other degenerative conditions, knee osteoarthritis may coexist with patellofemoral pain syndrome, particularly when both involve similar movement pattern dysfunctions.